Heidi L Weiss Selected Research

TVB-3664

1/2020	Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells.
1/2019	De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer.
5/2018	Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.

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Heidi L Weiss Research Topics

Disease

53	Neoplasms (Cancer) 10/2022 - 01/2004
19	Colorectal Neoplasms (Colorectal Cancer) 06/2022 - 05/2010
14	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2004
11	Colonic Neoplasms (Colon Cancer) 10/2022 - 02/2012
9	Breast Neoplasms (Breast Cancer) 01/2019 - 01/2002
5	Obesity 01/2022 - 01/2016
5	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2018 - 05/2013
4	Lung Neoplasms (Lung Cancer) 01/2019 - 01/2004
4	Carcinogenesis 01/2018 - 05/2011
4	Carcinoid Tumor (Carcinoid) 09/2015 - 03/2011
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 01/2016
2	Inflammation (Inflammations) 01/2020 - 10/2015
2	Lymphoma (Lymphomas) 01/2018 - 02/2012
2	Triple Negative Breast Neoplasms 07/2016 - 02/2015
2	Carcinoma (Carcinomatosis) 01/2016 - 01/2004
2	Adenocarcinoma 01/2016 - 03/2004
2	Hypoxia (Hypoxemia) 02/2015 - 03/2008
1	Adenoma (Adenomas) 06/2022
1	Glioblastoma (Glioblastoma Multiforme) 01/2022
1	Ulcerative Colitis 01/2021
1	Circulating Neoplastic Cells 01/2021
1	Crohn Disease (Crohn's Disease) 01/2021
1	Dysbiosis 01/2020

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2004
9	Fatty Acids (Saturated Fatty Acids)IBA 10/2022 - 08/2015
7	Fatty Acid Synthases (Fatty Acid Synthase)IBA 06/2022 - 03/2012
7	CateninsIBA 01/2021 - 02/2012
7	NeurotensinIBA 01/2021 - 03/2015
7	EnzymesIBA 10/2020 - 03/2012
6	Calcibiotic Root Canal SealerIBA 08/2015 - 03/2004
5	Messenger RNA (mRNA)IBA 01/2021 - 05/2011
5	Hormones (Hormone)IBA 01/2020 - 04/2004
4	Phosphotransferases (Kinase)IBA 01/2019 - 05/2011
3	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 11/2007
3	Protein Isoforms (Isoforms)IBA 01/2021 - 04/2004
3	TVB-3664IBA 01/2020 - 05/2018
3	Estrogen ReceptorsIBA 01/2019 - 04/2004
3	LipidsIBA 05/2018 - 08/2015
3	TOR Serine-Threonine KinasesIBA 09/2012 - 05/2010
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 09/2012 - 05/2010
2	Biomarkers (Surrogate Marker)IBA 11/2020 - 01/2004
2	Small Interfering RNA (siRNA)IBA 01/2020 - 09/2014
2	Adenosine Triphosphate (ATP)IBA 10/2019 - 01/2019
2	AMP-Activated Protein KinasesIBA 01/2019 - 01/2017
2	Pharmaceutical PreparationsIBA 10/2018 - 11/2013
2	Peptides (Polypeptides)IBA 01/2016 - 04/2011
2	RNA (Ribonucleic Acid)IBA 02/2015 - 01/2003
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2014 - 03/2008
2	Sirolimus (Rapamycin)FDA Link 09/2012 - 07/2011
2	Progesterone Receptors (Progesterone Receptor)IBA 03/2010 - 04/2004
2	LigandsIBA 03/2010 - 11/2004
2	Chimeric Antigen ReceptorsIBA 11/2008 - 06/2007
2	Interleukin-2 (IL2)IBA 03/2008 - 06/2007
2	Progesterone FDA LinkGeneric 11/2004 - 01/2002
2	Tamoxifen FDA LinkGeneric 11/2004 - 04/2004
1	villinIBA 06/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Sirtuin 2IBA 01/2021
1	Bile Acids and Salts (Bile Acids)IBA 01/2021
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 10/2020
1	Class 2 Receptor-Like Protein Tyrosine PhosphatasesIBA 10/2020
1	Oleic Acid (Oleate)IBA 01/2020
1	SurvivinIBA 01/2020
1	DefensinsIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2019
1	Transcription Factors (Transcription Factor)IBA 10/2019
1	Mitochondrial DNA (mtDNA)IBA 10/2019
1	dihydrosphingosine 1-phosphateIBA 01/2019
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2019
1	FND-4bIBA 01/2019
1	Electron Transport Complex I (NADH-CoQ Reductase)IBA 01/2019
1	sphingosine kinaseIBA 01/2019
1	HexokinaseIBA 01/2019
1	SphingosineIBA 01/2019
1	GelatinIBA 01/2019
1	SphingolipidsIBA 01/2019
1	S100 Calcium-Binding Protein A4IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2019
1	WortmanninIBA 10/2018
1	PolymersIBA 10/2018
1	CDw17 antigen (lactosylceramide)IBA 05/2018
1	Phospholipids (Phosphatides)FDA LinkGeneric 05/2018
1	SphingomyelinsIBA 05/2018
1	Adenine NucleotidesIBA 05/2018
1	Chloroquine (Aralen)FDA LinkGeneric 05/2018
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 05/2018
1	Capecitabine (Xeloda)FDA Link 01/2018
1	MTOR InhibitorsIBA 01/2018
1	CatalaseIBA 01/2018
1	CarcinogensIBA 01/2018
1	SuspensionsIBA 01/2018
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2018

Therapy/Procedure

16	Therapeutics 01/2022 - 01/2004
5	Drug Therapy (Chemotherapy) 10/2018 - 04/2005
3	Precision Medicine 05/2018 - 11/2013
1	Immunotherapy 01/2022
1	Ketogenic Diet 01/2022
1	Radiotherapy 01/2018